Clarisen Research

Clarisen Research (formerly ScienceMamasHQ Research) grew out of lived experience — a response to our children’s complex health challenges that weren’t resolved through conventional care. Along the way, we uncovered a pattern: nutrient deficiencies and metabolic imbalances were quietly affecting countless families, yet remained largely unrecognised by mainstream systems.

Clarisen Research was created to explore these overlooked connections with scientific rigour. Our work centres on how nutrition, thyroid and gut health intersect in the context of chronic and neurodevelopmental conditions. By bridging personal insight with evidence-based inquiry, we aim to expand the knowledge base, challenge assumptions, and improve outcomes for families navigating similarly complex health journeys.

Our Vision

At Clarisen Research, we are driven by a mission to uncover the root causes and ripple effects of modern-day malnutrition through rigorous, interdisciplinary science. We aim to clarify how nutrient deficits and imbalances contribute to a wide range of chronic, complex, and under-recognised conditions — especially in vulnerable and underserved populations.

Our vision is to produce actionable, high-quality evidence that empowers families, informs public health, and helps shape more equitable, effective models of care.

Our Research Goals

1. Drive Pioneering Studies
We aim to fund and lead innovative research exploring the nutritional needs and health outcomes of children and parents — with a particular focus on autism, histamine intolerance (HIT), mast cell activation (MCAS), food sensitivities, and other chronic or complex health conditions. Our work prioritises the role of essential nutrients in these populations.

2. Generate New Research Questions
Our research is designed to spark new hypotheses by mapping the links between nutrition, thyroid function, gut health, and immune/metabolic regulation — especially in families facing overlooked or misunderstood health concerns.

3. Conduct Longitudinal Investigations
We seek to establish long-term studies that track the outcomes of nutritional interventions across key developmental windows, with a focus on prevention, symptom resolution, and health resilience.

4. Enable Interdisciplinary Collaboration
We actively collaborate with researchers, clinicians, educators, and advocacy groups to co-create a deeper understanding of complex health conditions through a nutritional systems lens.

5. Translate Research into Practice
We are committed to turning insights into action by helping to shape evidence-based guidance for healthcare providers, caregivers, and educators working with neurodivergent children and families impacted by chronic health issues.

Our Evolving Research Focus

At Clarisen Research, we are committed to advancing scientific understanding of modern-day malnutrition and its widespread, under-recognised impacts on health — particularly in families, children, and underserved populations. Our work centres on exploring how nutrient deficiencies and imbalances interact within the body’s complex biological networks to influence both short- and long-term health outcomes.

1. Mapping Nutrient Interactions and Systems Biology

We investigate how key nutrients — including minerals, vitamins, and cofactors — influence and regulate one another across metabolic pathways.

Our research explores:

The synergistic and antagonistic relationships between essential nutrients such as iodine, selenium, magnesium, iron, zinc, molybdenum, and the B vitamin family.
How these interactions impact thyroid function, gut health, mitochondrial activity, redox balance, detoxification, and the body's stress and immune responses.
Nutrient interdependencies that may not be evident through conventional testing, especially in the context of chronic symptoms or unexplained health conditions.

2. Understanding Functional Deficiencies Beyond Bloodwork

Many individuals suffer from nutrient imbalances even when standard lab results appear “normal.” We aim to:

Investigate how nutrient activation, transport, and cellular uptake may be disrupted — creating hidden “functional” deficiencies.
Identify biomarkers and patterns that better reflect biological function rather than just nutrient presence in the bloodstream.
Explore how these subtle imbalances contribute to symptoms like fatigue, stunted growth, hormonal dysregulation, neurodevelopmental challenges, and metabolic dysfunction.

Our research will span:

Nutritional intervention studies
Biochemical and pathway modelling
Clinical trials and observational studies
Cross-disciplinary collaborations with endocrinology, gastroenterology, immunology, and public health

By unravelling these complex nutritional dynamics, we hope to bridge the gap between lived experience and science — making it possible for more families to access evidence-based insights, meaningful care, and effective prevention strategies.